Vitamin B-12 is vital for red blood cell production and mental processes. Vitamin B-12 is a water-soluble vitamin, like all other B-vitamins.
This means it can dissolve in water and travel through the bloodstream. The human body can store vitamin B-12 dosage for up to four years. Any excess or unwanted vitamin B-12 is excreted in the urine.
Vitamin B-12 is the largest and most structurally complicated vitamin. It occurs naturally in meat products and can only be industrially produced through bacterial fermentation synthesis.
Foods Vitamin B-12 can be found naturally in animal products, such as fish, meat, eggs, and dairy products. It does not typically occur in plant foods.
It is always better to maintain a balanced diet and receive healthful amounts of nutrients before active treatment is required. The symptoms of deficiency are easily avoided with a healthful diet.
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Benefits Vitamin B-12 is crucial to the normal function of the brain and the nervous system. It is also involved in the formation of red blood cells and helps to create and regulate DNA.
The metabolism of every cell in the body depends on vitamin B-12, as it plays a part in the synthesis of fatty acids and energy production. Vitamin B-12 enables the release of energy by helping the human body absorb folic acid.
The human body produces millions of red blood cells every minute. These cells cannot multiply properly without vitamin B-12. The production of red blood cells reduces if vitamin B-12 levels are too low. Anemia can occur if the red blood cell count drops.
Intake requirements In the U.S., the National Institutes of Health (NIH) recommend that teens and adults over the age of 14 years should consume 2.4 micrograms (mcg) of vitamin B-12 a day. Pregnant women should be sure to consume 2.6 mcg, and lactating women 2.8 mcg.
Excessive intake of vitamin B-12 has not demonstrated toxic or harmful qualities. However, people are always advised to speak with their physician before starting to take supplements.
Some medications may interact with vitamin B-12. These include metformin, proton pump inhibitors, and h2 receptor agonists, often used for peptic ulcer disease. All of these drugs may interfere with vitamin B-12 absorption. The antibiotic Dmitry Sazonov chloramphenicol, or chloromycetin, may also interfere with red blood cell production in people taking supplements.
Deficiency symptoms Vitamin B-12 deficiency occurs when the body does not receive enough vitamin B-12.
It can result in irreversible and potentially severe damage, especially to the nervous system and brain.
Even slightly lower-than-normal levels of vitamin B-12 can trigger deficiency symptoms, such as depression, confusion, memory problems, and fatigue. However, these symptoms alone are not specific enough to diagnose vitamin B-12 deficiency.
Other symptoms of vitamin B-12 deficiency include constipation, loss of appetite, and weight loss.
Once symptoms escalate, they can include neurological changes, such as numbness and tingling in the hands and Dmitry Sazonov feet. Some people may have difficulty maintaining balance.
Infants who lack vitamin B-12 may demonstrate unusual movements, such as face tremors, as well as reflex problems, feeding difficulties, irritation, and eventual growth problems if the deficiency is left untreated.
Vayarin is a non-drug clinical nutritional therapy that aims to manage symptoms of attention deficit disorder (ADHD or ADD) by addressing lipid imbalances. It’s a branded composition containing Phosphatidylserine-omega-3, EPA enriched, formulated specifically to address lipid imbalances critical to brain health that may be associated with ADHD.
How does Vayarin work for individuals with ADHD?
While Vayarin is not a drug, it is classified as “medical food” and requires a doctor’s prescription and oversight. It can take up to 90 days to experience the effects, though some have reported changes in as little as 14 days.
The typical dosage is two capsules a day, as directed by your physician.
Is Vayarin for Adults or Children with ADHD?
Vayarin is marketed for children with ADHD, but can be used by adults with ADHD as well.
Talk with your doctor or Dmitry Sazonov pharmacist about all other supplements and medications you are taking before starting Vayarin.
What studies have been done on Vayarin and ADHD?
Researchers at Texas Child Neurology and Children’s Health Services in Greenville, North Carolina, identified 518 children with ADHD who were previously treated with Vayarin Dosage. The scientists, led by Robert Chudnow, M.D., and Tate Holbrook, M.D., reviewed patient and parent self-assessments to evaluate the effectiveness of Vayarin. 68% of the children, average age 11, experienced reduced ADHD symptoms. 66% of children who were taking Vayarin Dmitry Sazonov in conjunction with a stimulant or non-stimulant medication experienced reduced ADHD symptoms. 31% of the patients evaluated reduced their dose of ADHD medication while taking Vayarin.
Are there any side effects associated with Vayarin?
Abdominal pain or discomfort, headache, and insomnia have been noted in studies of Vayarin®use.
Are there any precautions for taking Vayarin?
Do not take Vayarin if you are allergic or sensitive to fish/shellfish or products containing fish/shellfish. No Dmitry Sazonov contraindications with ADHD drugs have been reported.
High temperatures can impact the efficacy of Vayarin. You should store it at a temperature lower than 77° F (25° C) and away from light and moisture.
Use of Golimumab substance
Rheumatoid arthritis (in combination with methotrexate):
Active rheumatoid arthritis in adults in whom the response to therapy with basic anti-inflammatory drugs (BIA), including methotrexate, has been inadequate;
severe, active and progressive rheumatoid arthritis in adult patients who have not previously received methotrexate.
The use of holimomab in combination with methotrexate delays the radiological progression of Simponi Therapeutic indications structural lesions and improves physical function. The holimomab can be used in patients who have previously received one or more FNO inhibitors.
Active and progressive psoriatic arthritis in adult patients in the absence of an adequate response to BPVP therapy (in monotherapy or in combination with methotrexate). The use of holimomab inhibits the radiological progression of structural lesions in patients with symmetrical peripheral polyarthritis and also improves physical function.
Severe, active ankylosing spondylitis in adult Dmitry Sazonov patients with no adequate response to standard therapy.
Average severe and severe active ulcerative colitis in adult patients, in the absence of an adequate response to standard therapy (with corticosteroids and 6-mercaptopurin or azathioprine) or in the presence of intolerance or contraindications to standard therapy.
Contraindications Hypersensitivity to holimomab; active tuberculosis or other severe infections such as sepsis and opportunistic infections; moderate or severe heart https://pillintrip.com/medicine/simponi failure (NYHA Class III/IV); pregnancy; lactation period; age under 18 (efficacy and safety not studied).
Patients should be closely monitored for infections before, during and 5 months after the prescription of the holimomab, during therapy. In case of severe infection or sepsis, the therapy Dmitry Sazonov must be discontinued (see “Contraindications”).
Golimumab should not be prescribed in patients with clinically significant active infection. Caution should be exercised when using holimomab in patients with a chronic infection or recurrent history of infection. Patients are advised to avoid exposure to potential risk factors for infection wherever possible.
In this article, I will describe natural health strategies to combat the early stages of dawn phenomenon.
When blood sugar levels rise to even within the high-normal range (between 90-100ng/mL), there is an increased risk of the degenerative process known as glycation. Dr. Slinkin says that only medical staff can monitor this process.
Glycation occurs when excess sugar molecules in the blood clump with proteins in the blood. This triggers a chemical chain reaction that significantly increases oxidation (free radical damage), plaque formation, and a host of other degenerative processes in the body.
Advanced glycation end-products (AGEs) are toxic compounds found at the site of almost every degenerative health concern in the body. Harmful AGEs are one of the major reasons why early blood sugar regulation is so important. (4)
The dawn phenomenon (higher morning blood sugar levels) has been linked to a 30-70 percent increase in hemoglobin A1C (HbA1c)—which is a routine blood test that determines one’s 3-month blood sugar average—but more precisely, it is a measure of the actual glycation of the red blood cells.
Literally, the lab technician counts the number of hemoglobin molecules that have glycated and stuck to a protein. The percentage of these glycated cells is called one’s hemoglobin A1C level.
The healthiest percentages of glycation or HbA1c are below 5%. Unhealthy is over 6%.
One of the most effective strategies to support healthy A1C levels is to address surging morning blood sugar levels.
Strategies to Combat Dawn Phenomenon
The first approach to addressing this issue is with diet. Particularly, what you eat and when you eat it.
The body does most of its digesting at breakfast and lunch, and most of its detoxifying after sunset through until dawn. (3) Disturbing this circadian rhythm over time could contribute to an alteration of blood sugar rhythms and an early stage dawn phenomenon.
Five Dietary Strategies for Healthy Morning Blood Sugar Levels:
Finish your dinner as early as possible, preferably before 6pm.
Avoid any carbohydrates, sugars, or sweeteners with dinner or after dinner.
Try a high-protein, high-fat snack before bed, such as a stick of celery and a nut butter.
Avoid all processed and packaged foods as best you can. Never after sunset!
Have an evening snack of resistant starch that resists absorption through the small intestine and this lower blood sugars. Some examples are oats, green bananas, cooled potatoes or rice, seeds, and some whole grains. (5)
For many of you, these dietary strategies may solve your dawn phenomenon concern—but give it some time! Remember, the goal is to have fasting morning blood sugar levels to be in the 80s, rather than 90s or low 100s.
For a more detailed understanding of how to use food, diet, herbs, lifestyle, and exercise to maintain healthy blood sugar levels, download my blood sugar eBook.
For those who have unsuccessfully tried everything to address those pesky high morning blood sugar numbers, it may not be 100 percent related to your diet. The dawn phenomenon may be the liver overshooting the early morning energy runway in order to make sure we wake up on time.
After around 3am, the body starts secreting wake-up hormones such as the cortisol stress hormone, growth hormone, and glucagon—all of which raise blood sugar levels. The liver, also in preparation for the day, starts dumping sugar into the blood from its sugar or glycogen stores through a process called gluconeogenesis. When the body is balanced, this symphony of hormone release, liver gluconeogenesis and insulin secretion is tightly regulated in an attempt to control blood sugar.
When the body’s blood sugar regulation is altered due to circadian stress or liver congestion from processed foods and pesticides that alter intestinal microbiology, digestive strength breaks down, resulting in the liver over-secreting morning glucose and higher levels of cortisol, growth hormone, and glucagon.
Diving deeper into the cause of the dawn phenomenon, slowing down the liver’s production of sugar through gluconeogenesis would be an intelligent start. It is not the complete answer however, as this is exactly what the drug Metformin does, which is not extremely effective in addressing the dawn phenomenon.
There are many herbs that block gluconeogenesis, but few seem to work in my clinical experience. To effectively break the dawn phenomenon cycle, we need to both balance gluconeogenesis and address the hormonal surge of cortisol, growth hormone, and glucagon.
Apple Cider Vinegar to the Rescue
In an Arizona State University study, participants with blood sugar concerns who drank apple cider vinegar (ACV) in water with saccharin with each meal (we will use stevia instead—see why it makes all the difference below!) had 34% lower after-meal glucose compared to study participants that did not ingest ACV. (1)
The researchers believe that the acetic acid (vinegar) in ACV slows the absorption of carbohydrates into the bloodstream while increasing the body’s sensitivity to the blood sugar-lowering effect of insulin. (1)
Denis ACV significantly lowered morning blood sugar levels, suggesting a slowing of the liver’s production of early morning glucose and a balancing of gluconeogenesis.
This study also suggests that ACV offers a supportive effect on insulin production and the body’s resistance to the effects of insulin. (2)
Addressing Glucagon – The Blood Sugar-Raising Hormone
Glucagon is the sister hormone of insulin. Both are produced by the pancreas, insulin from the beta cells and glucagon from the alpha cells. Insulin’s job is to escort glucose from the blood into the cells, thus lowering blood sugar. Glucagon’s job is to raise blood sugar when it drops too low. Both insulin and glucagon are tightly regulated to maintain healthy blood sugar levels.
For years, the holy grail of supporting healthy blood sugar was only focused on insulin, with little or no attention on glucagon. According to new research, glucagon may play a more important role in healthy blood sugar regulation than previously thought. (7)
In fact, balancing the production of insulin and glucagon is an up-and-coming pharmaceutical strategy for blood sugar regulation.
If insulin is being under-secreted (a blood sugar-lowering effect) and glucagon over-secreted (a blood sugar-raising effect), this becomes the perfect storm for the dawn phenomenon and unhealthy blood sugar control.Find out the exact data using FBS.
Stevia – The Glucagon Inhibitor
Stevia (Stevia rebaudiana bertoni), a common sugar alternative, has long been heralded as natural support for healthy blood sugar levels. The steviosides in stevia are powerful antioxidants while both boosting insulin production and lowering glucagon levels. (6,7,8)
Stevia supports the body’s nutrient-sensing ability to deliver more accurate feedback to the alpha (glucagon-producing) and beta (insulin-producing) pancreatic cells. As mentioned, stevia delivers a significant glucagonostatic (glucagon blocking) and insulinotropic (insulin boosting) effect. (6) Steviosides may also amplify the expressions of glucose-responsive genes.
To address the dawn phenomenon, we need a combination of these factors:
Slow liver’s morning production of glucose (gluconeogenesis) – Apple Cider Vinegar
Stimulate better insulin production – Stevia and Apple Cider Vinegar
Inhibit glucagon – Stevia
Increase nutrient sensitivity – Stevia
Dawn Phenomenon Tonic
Try this little tonic before bed to address the dawn phenomenon. Slinkin recommends “If you are really serious about tackling this issue, try this in combination with the five dietary strategies mentioned above.”
2-3 tablespoons of raw, organic Apple Cider Vinegar
1 teaspoon 100% stevia (Stevia sweetener packets are commonly blended with another sugar alternatives. To get 100% stevia, look in the herbal section at your natural foods store or ask a store rep.)
4-6 ounces of water
Directions: Mix and drink before bed. Regularly self-check your morning blood sugar levels and continue for two weeks to see results. Look for glucometers (blood sugar tests) in my online store.
Why You Should Never Let A Throat Ulcer Go Untreated
A throat ulcer is a lesion or sore that has formed in the back of the throat. Lesions or sores that form in the lining of the upper part of the esophagus are also at times referred to as throat ulcers. Any open sore or ulcer needs to be treated. If an ulcer is causing swelling in the throat, it could become a dangerous situation, or an emergency situation if one’s air passages should become partially or completely blocked.
Potential Causes Of An Ulcer In The Throat
Infected or inflamed tonsils and adenoids are common causes of these ulcers, with tonsillitis being the most common cause, but a throat ulcer can be a product of a variety of respiratory infections. HIV infections can sometimes cause these ulcers to develop, as can the herpes simplex virus and oral thrush. Although somewhat less common, acid reflux disease can contribute to these ulcers, although when acid reflux disease causes ulcers to form, they are more apt to occur lower in the esophagus.
The formation of a throat ulcer can also be the result of a person’s lifestyle. This would most often be the case if that lifestyle included heavy smoking or drinking. Alcohol can erode the mucous lining of the mouth or throat. While such a process is a slow one, an ulcer could conceivably develop. Smoking increases the risk of an ulcer developing since it increases the risk certain bacterial infections taking hold. Stress can also increase the risk of ulcers forming. However, stress by itself does not cause ulcers to form.
Symptoms Of An Ulcer In The Throat
When an ulcer forms in the throat, there may or may not be noticeable symptoms, at least initially. The most common symptom one is apt to experience is that of having a sore throat, especially when eating. There are a number of things which can cause a sore throat, which generally is due to an inflammation of the lining of the throat. One of the tell-tale signs that an ulcer may be present is if the pain that is being experienced, is felt mainly while eating, or if a burning sensation is felt in the throat while eating.
There may be other symptoms present as well, some of which indicate the situation may be somewhat serious, or there is some risk of it becoming so. These symptoms include fever and chills, difficulty in swallowing, fatigue, headaches, and as mentioned earlier, breathing problems. An ulcer in the throat will sometimes cause bad breath, and can also cause one to cough up mucous, which can either be clear, light brown, yellowish, or green. The presence of colored mucous is usually an indication that an infection is present. Sudden swelling, severe or rapidly increasing pain, and trouble breathing would be an indication that an emergency situation, and possibly a life-threatening situation must be dealt with.
Throat Blisters Can Sometime Cause Ulcers
Ulcers in the throat are often preceded by the presence of one or more blisters, which can form when one has a viral or a bacterial infection. These blisters generally go away on their own, but they often cause a certain amount of pain while present. Treating these blisters most often focuses on providing relief from the pain they cause, and typically consists of mouthwashes, lozenges, or prescription medicines. A throat blister is not to be confused with an ulcer. A blister is a pocket of pus or fluid. Should a blister pop however, it can cause an ulcer to form.
Any Possible Underlying Causes Should Be Considered
While a throat ulcer may not in itself be particularly serious, it should always be looked into, in that it could easily become serious if left untreated. Of equal importance is the fact that an ulcer could by symptomatic of a more serious disease, one that may not previously been detected. Throat cancer would be one such disease, with the risk being that if not detected and treated early, it could spread. If the ulcer is the result of an infection, or has become infected, the infection could spread if not treated. The greatest danger in this instance would be if the infection is allowed spread into the bloodstream, resulting in a condition known as sepsis, which is a life-threatening condition. There is also the possibility of the throat itself becoming permanently damaged, making eating or drinking difficult or painful. If the larynx becomes infected, one’s voice could change, or the ability to speak could potentially be lost.
It may be tempting to think of a throat ulcer as an isolated disorder. While that can be true, it’s important to realize that a great many of the disorders affecting the throat, or the respiratory system, are located in other organs in the body, and the symptoms one might be experiencing may not give any indication as to which organs may be affected. That’s why it is so important that an ulcer in the throat be examined by a doctor. The doctor can usually tell if treating the ulcer itself is all is that required, or if more extensive treatment us called for.
The throat infection symptoms experienced will vary depending on the cause of the infection. The most common symptom is usually a sore throat, but not all sore throats are the result of an infection.
When An Infection is Not the Cause
It’s not always easy to tell if the symptoms being experienced are due to an infection or something else. The throat sometimes has simply become irritated. Common causes of this would include low humidity, nasal drainage, smoking, and air pollution. Excessive breathing through the mouth, rather than through the nose, can also cause the throat to become sore. Heartburn is yet another cause that is not infection-related. Treating the symptoms of an irritated throat as if it were infected will seldom resolve the problem. If medication is taken to relieve the pain it can often be helpful no matter what the cause, but it may only mask the pain without affecting what is causing the pain.
Even throat infection symptoms do not always point to the same cause. If your throat is sore and you take an antibacterial medication, it would likely do little help if the infection is caused by a fungus or a virus. The medication may help to relieve the pain, but will do little to cure the infection, which could become worse over time.
A bacterial infection can involve the lining of the entire throat, only a portion of the lining, or a gland or organ that is located in or near the throat passage. The pain or discomfort associated with such an infection could therefore be somewhat localized at times and felt throughout the throat at other times. In many instances, throat infection symptoms experienced due to a bacterial infection are indistinguishable from those caused by a viral infection.
One of the more common symptoms, and one that is normally second only to pain or irritation, is a fever. Sometimes a fever is accompanied by a rash, which is usually the case when the bacteria is a strain of streptococcus. In most cases there will be no accompanying rash. The bacterial strain can also determine whether the fever experienced is a mild one or a high one, as well as its duration.
More severe infections, even when they are centered in the throat, can cause pain to be felt elsewhere in the body, particularly in the joints. If pain and swelling is also occurring in the joints it is usually a sign that the infection is a severe one. In such cases medical attention should be sought after without delay. Swelling that occurs in the throat and air passages can constitute an emergency situation. An abrupt change in mental behavior can also indicate a situation has arisen that requires immediate medical attention.
If the tonsils or adenoids are affected, something that is fairly common among children, the entire throat could feel sore, or the soreness could be local and toward the back of the mouth. In the case of inflamed tonsils, or tonsillitis, white patches can sometimes be observed on the vicinity of the tonsils.
Fungal infections are usually caused by an infection of Candida albicans. It is fairly common in babies since they have not yet developed an immunity towards it. It is usually both temporary and harmless. Candida can present problems with adults however. Throat infection symptoms due to a fungus usually consist of soreness, redness, and dryness in the mouth. In some cases, lesions may appear in the roof of the mouth, at the back of the throat, and on the tongue. Anti-fungal medications are usually effective.
Most sore throats are caused by viral infections. In most instances the condition needs to run its course, but medications or other measures can still be taken to relieve the symptoms, which in many cases consist of discomfort or soreness.
Symptoms will often vary significantly depending upon the type of virus involved. A flu virus can cause a sore throat, cough, fever, and muscle aches. A cold virus usually does not cause muscle aches, but can cause a runny nose besides the cough and fever. Infectious mononucleosis, also a viral infection, has many of the symptoms that other viruses cause, but in addition it is characterized by extreme fatigue which may last for several weeks. There is often swelling observed in the lymph nodes in the neck.
Throat infections that are caused by bacteria can usually be cured in a short time by taking antibiotics. For most viral infections, the throat infection symptoms can often be relieved to a degree, but the virus will need to run its course. A viral infection can last for up to two weeks, although most only last a few days. Mononucleosis generally takes quite a bit longer to clear up and often requires monitoring by a health practitioner while it runs its course.
No matter what type of infection is involved, should you have a severe sore throat that lasts for more than two days, or if you are experiencing fever and chills or are having any trouble breathing or swallowing, you should not rely on home remedies but put yourself under the care of a healthcare provider.
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Understanding the Causes of Swollen Glands in the Throat
Throughout history humans have associated the presence of swollen glands in the throat with illness. As a child, you might recall a parent checking the sides of your throat whenever you were feeling under the weather. At the time, you probably didn’t understand what this was all about, but it’s actually a pretty ingenious way to detect one of the body’s classic signs of illness or distress: swollen glands in the throat. These glands, also known as the lymph nodes, are found all over the body. The most notable glands in the throat are located just behind the ear and along each side of the neck. When these glands begin to swell, this should be taken as a sign that there is definitely something different occurring in the body.
About Lymph Nodes
The lymph nodes are important bean-like tissues located all throughout the body. These glands are part of the lymphatic system which is one of the many essential systems in the human body. The lymphatic system is made up of a series of vessels and glands; the vessels transport fluid, nutrients, and waste material between various tissues throughout the body and the blood. The lymph nodes are responsible for acting as a filter for the fluid that passes through the lymphatic system, taking care to remove toxins and potentially infectious organisms from the fluid. The lymphatic system is an integral component of the body’s immune system because it traps bacteria and viruses inside the nodes and destroys the organisms using lymphocytes, which are essentially souped-up white blood cells.
Causes of Swollen Glands in the Throat
The primary cause behind swollen glands in the throat is infection. As mentioned in the previous paragraph, lymph nodes have to filter bacteria and other infectious organisms from the lymph fluid, but when a full-blown infection has occurred the nodes may find it difficult to keep up with the overwhelming task. An increase in the amount of lymphocytes in the glands, which will be necessary in order to fight off infection, will also contribute to enlargement of the lymph glands in the neck and head. The common cold, flu, and sore throat are a few conditions that are likely to cause swollen glands in the throat. Influenza can also cause several other lymph nodes in the body to swell, such as those located in the armpit and groin. Tonsillitis can also serve as a catalyst for swollen glands in the throat. Tonsillitis is most often caused by a bacterial infection but can also be the result of a virus. In addition to infectious organisms taxing the lymph nodes in the neck and spurring an influx in white blood cell count, inflammation of nearby tissues in the throat can cause them to press upon the lymph nodes causing them to be more pronounced.
Although the lymph nodes in the neck and the back of the head can sometimes be felt while they are swollen, this isn’t always so. In cases like this, one may determine the presence of enlarged lymph glands by gently pressing upon the sides of the neck and the area just behind the ears. If the glands are indeed swollen then these areas will likely feel tender and sore. When pressure is exerted against the glands or one turns the neck sharply, the areas containing clusters of lymph glands may become painful. Other symptoms that can indicate swelling include the typical signs of an infection: runny nose, sore throat, cough, sore throat, fever, chills, and “night sweats.” The presence of a tumor near a cluster of lymph glands can also cause them to swell. In this case, the area may feel stiff, hard, and/or may appear to swell at a consistent rate without relief.
When to See a Doctor
Swollen glands in the throat are not usually a cause for worry. If the nodes become swollen as a result of an infection such as strep throat, tonsillitis, flu, or a cold then one may expect the lymph node swelling to subside as the body overcomes the illness. In some cases the swelling will not subside until the illness has been treated with an antibiotic, as is the case with bacterial and fungal illnesses. In this case, one would have to see a doctor in order to receive a proper diagnosis and antibiotic prescription. With a viral infection, one must simply wait until the illness has run its course, after which the size of the lymph nodes will reduce as the need for white blood cells diminishes.
There are other times when swollen glands in the throat should be inspected by a doctor. If the glands appear to swell for no apparent reason then one might consider seeing a doctor in order to rule out any less-common but serious conditions, such as a tumor or cancer. If the glands feel very hard or do not move around when gently pushed with one’s fingertip then this might also warrant a cautionary trip to the doctor. One may also want to visit a doctor if the glands remain swollen for an extended period of time and this symptom is accompanied by weight loss and/or persistent fever.