Euphon Codeine (Euphon Syrup) is an opioid pain medication.
Euphon Codeine (Euphon Syrup) is an opioid pain medication.

Euphon Codeine (Euphon Syrup) is an opioid pain medication. An opioid is sometimes called a narcotic. Codeine (Euphon Syrup) is used to treat mild to moderately severe pain.

Codeine (Euphon Syrup) may also be used for purposes not listed in this medication guide.


An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.sponsored

Codeine (Euphon Syrup) sulfate is an opioid analgesic indicated for the management of mild to moderately severe pain where the use of an opioid analgesic is appropriate.


There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Use: Labeled Indications

Pain management: Management of mild- to moderately-severe pain

Limitations of use: Reserve Codeine (Euphon Syrup) for use in patients for whom alternative treatment options (eg, nonopioid analgesics, opioid combination products) are ineffective, not tolerated, or would be otherwise inadequate.

Off Label Uses

Cough in select patients

In a metaanalysis of trials evaluating the treatment of chronic cough, the use of Codeine (Euphon Syrup) demonstrated efficacy in patients with this condition.


An opioid analgesic related to morphine but with less potent analgesic properties and mild sedative effects. It also acts centrally to suppress cough. [PubChem]


Dosage Forms

Excipient information presented when available (limited, particularly for generics); consult specific product labeling.


Oral, as sulfate:

Generic: 15 mg, 30 mg, 60 mg

Dosing: Adult

Pain management (analgesic):

Injection [Canadian product]:

Opioid-naive patients: IM, SubQ: 30 to 60 mg every 4 to 6 hours as needed (use the lowest effective dose for the shortest period of time necessary)

Conversion from oral Codeine (Euphon Syrup) or another opioid: IM, SubQ: Refer to product labeling for dose conversions.

Oral: Note:

These are guidelines and do not represent the maximum doses that may be required in all patients. Doses should be titrated to pain relief/prevention.

Immediate release (tablet, oral solution [Canadian product]): Initial: 15 to 60 mg every 4 hours as needed; maximum total daily dose: 360 mg/day; patients with prior opioid exposure may require higher initial doses. Note: The American Pain Society recommends an initial dose of 30 to 60 mg for adults with moderate pain (American Pain Society 2016).

Controlled release: Codeine (Euphon Syrup) Contin [Canadian product]: Note: Titrate at intervals of ≥48 hours until adequate analgesia has been achieved. Daily doses >600 mg/day should not be used; patients requiring higher doses should be switched to an opioid approved for use in severe pain. In patients who receive both Codeine (Euphon Syrup) Contin and an immediate release or combination Codeine (Euphon Syrup) product for breakthrough pain, the rescue dose of immediate release Codeine (Euphon Syrup) product should be ≤12.5% of the total daily Codeine (Euphon Syrup) Contin dose.

Opioid-naive patients: Initial: 50 mg every 12 hours

Conversion from immediate release Codeine (Euphon Syrup) preparations: Immediate release Codeine (Euphon Syrup) preparations contain ~75% Codeine (Euphon Syrup) base. Therefore, patients who are switching from immediate release Codeine (Euphon Syrup) preparations may be transferred to a ~25% lower total daily dose of Codeine (Euphon Syrup) Contin, equally divided into 2 daily doses every 12 hours.

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